FIGURE 7
RT-PCR of human non-neoplastic pituitary and pituitary adenomas for Ptx1 mRNA. One non-neoplastic pituiary and all eighteen pituitary adenomas, containing six GH-secreting adenomas (G1-G6), two PRL-secreting adenomas (P1, P2), two ACTH-secreting adenomas (A1, A2), two TSH-secreting adenomas (T1, T2), two null cell adenomas (Nu1, Nu2), and four gonadotropin-subunit-positive adenomas (Gn1-Gn4), have expression of Ptx1 mRNA. Two of six GH-secreting adenomas (G4, G6) which were immunohistochemically negative for Ptx1 protein, also have expression of Ptx1 mRNA, but one of its two cases (G6) were faint signal for Ptx1 mRNA. RT(-) indicates a negative control without reverse transcription in human non-neoplastic pituitary.
