TABLE 3 Immunohistochemical Detection of Ptx1 Protein in Human Non-Neoplastic Pituitaries and Pituitary Adenomas

From: Expression of Pituitary Homeo Box 1 (Ptx1) in Human Non-Neoplastic Pituitaries and Pituitary Adenomas

Diagnosis

Number Studied

Number Positive (%) Ptx1 Protein

Non-neoplastic pituitaries

5

5 (100)

GH-secreting adenomas

14

10 (71.4)

PRL-secreting adenomas

12

12 (100)

ACTH-secreting adenomas

20

18 (90)

TSH-secreting adenomas

7

6 (85.7)

Non-functioning adenomas

20

17 (85)

Gonadotropin-subunit-positive adenomasa

10

9 (90)

Total

73

63 (86.3)

  1. aTen adenomas of clinically nonfunctioning adenomas immunohistochemically expressed one or more of FSHβ, LHβ, or α-SU, and were subclassified as gonadotropin-subunit-positive adenoma.
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