FIGURE 2 | Modern Pathology

FIGURE 2

From: Epithelioid Leiomyosarcoma in a Non-Immunocompromised Infant: Additional Differential Diagnosis of Pediatric “Round Cell Tumors”

FIGURE 2

A, histology of the tumor showing solid and epithelioid growth of polygonal cells. Note the vesicular nuclei and often vacuolated cytoplasm. Mitosis was occasionally seen (hematoxylin and eosin stain; original magnification, 100 ×; inset, 200 ×). B, positive immunostaining for MIC2 (hematoxylin counter-stain; original magnification, 200 ×). C, tumor cells demarcated by reticulin fibers in single cells (silver stain; original magnification, 100 ×). D, positive immunostain for smooth muscle actin (hematoxylin counterstain; original magnification, 200 ×).

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