TABLE 2 Summary of p53 Mutations

From: Correlation of p53 Mutations in ThinPrep-Processed Fine Needle Breast Aspirates with Surgically Resected Breast Cancers

Case Number

Exon

Codon

Sequence Change

Amino-Acid Change

Surgical

Cytology

    

20

13

5

*

del 23 bases

 

9

7

5

130

C→T

Leu→Phe

10

3

5

175

G→A

Arg→His

36

61

5

183

C→G

Ser→STOP

38

29

6

209

del 2 bases

 

13

19

6

220

A→C

Tyr→Ser

17

38

7

232

T→G

Ile→Ser

34

60

7

248

G→A

Arg→Gln

NA

59

8

270

T→C

Phe→Leu

NA

62

9

331

C→T

Gln→STOP

  1. **, deletion (del) starting at nucleotide residue 13041 in intron 4 and involving codons in exon 5.
  2. NA, tissue not available.
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