FIGURE 3
From: Cutaneous Dendritic Cells Are Main Targets in Acute HIV-1-Infection
A-F, Immunohistology: A, abundant epidermal and dermal CD3+ T cells (×20); B, most of the T cells are also GB-7 reactive, indicating an activated, cytotoxic T cell phenotype (×20). C, CD1a+ LC are significantly decreased and show degenerative morphologic changes (×40). D, abundant intraepidermal CD68+ cells, some of them with a dendritic shape. E, one LC reactive for anti-p24-antibody (×60). F, double staining of DC co-expressing CD1a (red staining) and p24 (blue staining); inset: GB-7+ cytotoxic T cells (red staining) in apposition with a p24-reactive DC (blue staining) (×60).
