TABLE 1 Summary of Clinical Features

From: HIV-Associated Multinucleated Giant Cells in Lymphoid Tissue of the Waldeyer's Ring: A Detailed Study

Case Number

Sex (M/F)

Age (Years)

Anatomic Location

Clinical Data

Ethnic Group/Mode of HIV Transmission

CD4 Count (μl)/viral load (copies/mL)*

HIV Status at Time of Biopsy**/Follow-Up

 1

M

38

Palatine tonsils

Enlargement

Caucasian/bisexual

110/NA

C/DOD within the year

 2

M

30

Adenoids

Mass, recurrent otitis

Caucasian/bisexual

NA/NA

NA/lost for follow-up

 3

M

36

Palatine tonsils

Enlargement

Caucasian/NA

NA/NA

NA/NA

 4

M

27

Adenoids

Enlargement

Caucasian/homosexual

NA/NA

A/AIDS 8 years later

 5

M

49

Palatine tonsils

Enlargement

Caucasian/homosexual

389/NA

B/alive

 6

F

48

Adenoids

Enlargement

African/heterosexual

226/NA

B/alive 2 years later, then lost for follow-up

 7

F

21

Adenoids, palatine tonsils

NA

African/heterosexual

<100/NA

B/alive

 8

M

29

Adenoids

Enlargement

Caucasian/homosexual

NA/NA

A/DOD 3 years later

 9

F

32

Adenoids

Enlargement, postnasal discharge

Caucasian/heterosexual

945/NA

A/alive

10

F

38

Adenoids, palatine tonsils

NA

African/heterosexual

135/NA

A/alive 1 year later

11

M

27

Palatine tonsils

NA

Caucasian/homosexual

62/NA

A/alive 1 year later

12

F

33

Adenoids

Enlargement

Caucasian/heterosexual

177/<4000

B/DOD 3 years later

13

M

28

Adenoids

Polypoid mass, otitis serosa

Caucasian/bisexual

229/70000

A/alive 1 year later

14

M

35

Adenoids, palatine tonsils

Enlargement, recurrent tonsillitis

African/heterosexual

426/10670

A/alive 1 year later

15

M

43

Adenoids, palatine tonsils

Enlargement

African/heterosexual

17/96459

C/alive

16

F

4

Adenoids

Enlargement, otitis serosa

African/feto-maternal

1280/<400

A/alive

17

F

4

Adenoids, palatine tonsils

Nasopharyngeal obstruction

African/feto-maternal

828/1298

A/B 1 year later

18

M

11

Adenoids, palatine tonsils

Enlargement

African/feto-maternal

343/119000

A/alive

19

M

6

Adenoids, palatine tonsils

Enlargement

African/feto-maternal

590/104000

A/alive

20

F

25

Adenoids

Slow growing mass

African/heterosexual

159/49500

A/alive

21

F

30

Adenoids

Enlargement

African/heterosexual

194/NA

A/alive

  1. NA, not available; DOD, dead of disease.
  2. *The viral load was determined by nucleic acid sequence based analysis (NASBA).
  3. **The HIV status at time of biopsy was defined according to the 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults (Centers for Disease Control and Prevention (CDC), MMWR 1992; 41(No. RR-17).