FIGURE 5 | Modern Pathology

FIGURE 5

From: Erratum: Malignant Peripheral Nerve Sheath Tumors with t(X;18). A Pathologic and Molecular Genetic Study

FIGURE 5

Case 2: Malignant peripheral nerve sheath tumor (MPNST) arising in a preexisting neurofibroma of the brachial plexus. A, low-power view shows normal nerve, neurofibroma, and MPNST components (hematoxylin and eosin). B, high-power view of MPNST shows cellular, mitotically active spindle cell sarcoma; C, junction of neurofibroma with MPNST. D, focal cytoplasmic CD57 immunoreactivity; E, diffuse membrane-associated collagen IV immunoreactivity.

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