TABLE 2 Immunohistochemistry of Cell Cycle Regulatory Proteins in Solid Pseudopapillary Tumor of the Pancreasa
Variable | Cyclin D1 | Cyclin D3 | p21 | p27 | p53 | mdm2 | MIB-1 |
---|---|---|---|---|---|---|---|
Patient A | 50% | 30% | 100% | 50–80% | — | 50% | — |
+++ | ++ | +++ | ++ | ++ | — | ||
Patient B primary tumor | 50% | <5% | 10% | 50–100% | — | 10% | <1% |
++ | ++ | +++ | ++ | ++ | |||
Metastasis | 30% | <5% | 10% | 30% | — | <5% | <1% |
++ | ++ | ++ | ++ | ++ | ++ |