FIGURE 4 | Modern Pathology

FIGURE 4

From: In Situ Hybridization and Reverse Transcription–Polymerase Chain Reaction for Cyclin D1 mRNA in the Diagnosis of Mantle Cell Lymphoma in Paraffin-Embedded Tissues

FIGURE 4

A, Polymerase chain reaction (PCR) results for the t(11;14) translocation. B, the nested PCR protocol was performed after the amplification for a c-erb-B2 sequence for the DNA control. Representative cases both from the study and control groups are shown. Lane 1: negative control; lanes 2–13: mantle cell lymphoma cases; lane 14: 50–base pair (bp) ladder; lane 15: marginal zone lymphoma; lane 16: lymphoblastic lymphoma; lane 17: B-cell chronic lymphocytic leukemia, representing the only positive case in the control group.

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