FIGURE 2 | Modern Pathology

FIGURE 2

From: Epstein-Barr Virus–Negative Hodgkin's Lymphoma After Mycosis Fungoides: Molecular Evidence for Distinct Clonal Origin

FIGURE 2

(A) Bone marrow infiltrate with small lymphoid cells and typical Hodgkin and RS-cells. The RS-cells were stained for CD30 (arrows). (B) the same CD30-stained area as in Panel A after LCM of CD30-positive RS cells (arrows). Note that the photograph is taken without cover slide in Panels A and B (×400). (C–E) Computer-assisted fragment length analysis (Genescan) of three different groups of microdissected CD30-positive RS cells with identical biallelic rearrangements for the IgH gene. (F) Corresponding rearranged IgH gene sequences obtained from microdissected cells.

Back to article page