FIGURE 1
From: How Familial Cancer Genes and Environmentally Induced Oncogenes Have Changed the Endocrine Landscape

A patient with familial medullary carcinoma of thyroid usually has C cell hyperplasia in the contralateral lobe. A, Sometimes the hyperplastic foci are obvious and the diagnosis of a familial disorder is readily proven. B, In some patients, C cells are numerous, but the criteria for a diagnosis of hyperplasia are difficult to prove.