TABLE 2 Subclassification of 139 Fine-Needle Aspiration Biopsy Cases of Lymphoma With or Without Flow Cytometry Analysis Before and After Review of Unclassified Cases

From: Fine-Needle Aspiration Biopsy in the Diagnosis and Classification of Primary and Recurrent Lymphoma: A Retrospective Analysis of the Utility of Cytomorphology and Flow Cytometry

Lymphoma

Total Cases

Positive—all Cases, n (%)

Subclassified in report—all cases, n (%)

Subclassified after review—All Cases, n (%)

Positive—with FCM, n (%)

Subclassified in Report—with FCM, n (%)

Subclassified after review with FCM, n (%)

HD

16

7 (44)

7 (100)

7 (100)

N/A

N/A

N/A

SLL/CLL

9

9 (100)

9 (100)

9 (100)

9/9

9 (100)

9 (100)

LPL

4

3 (75)

3 (100)

3 (100)

3/3

3 (100)

3 (100)

Plasmacytoma

5

5 (100)

4 (80)

5 (100)

4/4

3 (75)

4 (100)

MZL

15

7 (47)

1 (14)

2 (28)a

6/13 (46)

1 (17)

2 (33)

FL

22

15 (68)

10 (67)

13 (87)b

13/15 (87)

10 (77)

13 (100)

MCL

2

2 (100)

1 (50)

1 (50)

1/1

1 (100)

1 (100)

DLBCL

34

26 (76)

14 (54)

21 (81)c

21/24 (88)

13 (62)

20 (95)

BL

2

2 (100)

2 (100)

2 (100)

2/2

2 (100)

2 (100)

PTCL

5

3 (60)

3 (100)

3 (100)

3/4 (75)

3 (100)

3 (100)

ALCL

2

2 (100)

1 (50)

1 (50)

N/A

N/A

N/A

Subtotal

116

81 (70)

55 (68)

67 (83)

62/78 (80)

45/62 (73)

57/62 (92)

Unclassifiable

23

12 (52)

     

TOTAL

139

93 (67)

55 (59)

67 (72)

74/90 (82)

45/74 (61)

57/74 (77)

  1. aSlides not available for review on 4/6 unclassified cases.
  2. bSlides not available for review on 2/5 unclassified cases.
  3. cSlides not available for review on 3/12 unclassified cases.
  4. HD, Hodgkin's disease; SLL, small-lymphocytic lymphoma; CLL, chronic lymphocytic lymphoma; LPL, lymphoplasmacytic lymphoma; MZL, marginal-zone B-cell lymphoma; FL, follicle-center lymphoma; MCL, mantle cell lymphoma; DLBCL, diffuse large B-cell lymphomas; BL, Burkitt's lymphoma; PTCL, peripheral T-cell lymphoma; ALCL, anaplastic large-cell lymphoma.
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