TABLE 1 Chromosome Copy Number Distribution and Ploidy Pattern in Osteosarcoma Cell Lines According to Metaphase or FISH Analysis

From: Simultaneous Paired Analysis of Numerical Chromosomal Aberrations and DNA Content in Osteosarcoma

Cell Line

Metaphase Analysis

FISH Analysis Most Recurrent Signal Copy Number (Chromosome)

Ploidy Pattern by FISH

 

Ploidy Pattern (Median Number of Metaphase Chromosomes)

CIa

1

7

8

12

16

17

18

 

IOR/OS9

Near-diploid (50)

1.1

4

2

4

2

2

2

2

Near-diploid

IOR/OS10

Near-triploid (56)

1.2

3

3

3;4

2

2

3

3

Near-triploid

IOR/OS14

Near-triploid (61)

1.3

3

3

3

2

2

3;4

3

Near-triploid

IOR/OS15

Near-triploid (62)

1.4

3

6

3

3

2

3;6

3

Near-triploid

SARG

Near-triploid (55)

1.2

4;5;6

4

4;5

4;6

4

4

3

Near-tetraploid

IOR/MOS

Near-diploid (52)

1.1

4

2

2

2

2

2

2

Near-diploid

  1. aCI, chromosome index; (calculated by dividing the median chromosome number by 46); FISH, fluorescence in situ hybridization.
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