FIGURE 2
From: Mixed Conventional and Desmoplastic Infantile Ganglioglioma: an Autopsied Case with 6-Year Follow-Up
Biopsy specimen at 3 1/2 months of age. A, A fascicular and somewhat storiform pattern of growth typifies the tumor. Occasional ganglion-like cells are evident (arrows) (H&E). B, A 1-μm toluidine blue–stained preparation demonstrates tubular structures (large arrows) surrounded by dark, bipolar fibroblasts with elongate processes. Smaller arrows indicate probable neuronal or “ganglion-like” cells within the stroma. C, Reticulin staining shows intense desmoplasia. Note that tubular and insular structures lack staining. D, GFAP immunoreactivity is present within tubular structures and in a fraction of the spindle cells enmeshed in collagenous stroma.
