FIGURE 3
From: Identification of the Target Cells of Orientia tsutsugamushi in Human Cases of Scrub Typhus
O. tsutsugamushi in an endothelial cell of a myocardial capillary. A, The capillary endothelial cell contains several bacteria in its cytoplasm (arrows). One bacterium appears to be budding from the endothelial cell surface (arrowhead). E-erythrocyte in the capillary lumen. Bar = 1 μm. B, Higher magnification of a budding Orientia cell, surrounded by the plasma membrane (arrows) of the endothelial cell. Bar = 0.5 μm. C, Part of the cell wall of the rickettsia shown in Figure 3B demonstrating a thicker outer leaflet of the cell wall (arrowhead). Arrow indicates host cell membrane surrounding the bacterium. Bar = 1 μm. D, Part of an envelope of an orientia in another endothelial cell showing thicker outer leaflet of the outer membrane of the cell wall (arrowhead) and a cytoplasmic membrane (arrow). Bar = 1 μm.
