FIGURE 1
From: Expression of Neuro D1 in Human Normal Pituitaries and Pituitary Adenomas
RT-PCR for Neuro D1 mRNA of 19 human pituitary adenomas, containing three ACTH-secreting adenomas (ACTH 1–3), five GH-secreting adenomas (GH 1–5), three PRL-secreting adenomas (PRL 1–3), four non-functioning adenomas (NF 1–4), and four gonadotropin-subunit-positive adenomas (Gn 1–4). Analysis of Neuro D1 mRNA demonstrated that the expected 447-bp PCR product was detected in all 3 ACTH-secreting adenomas and 6 of 8 non-functioning adenomas (3 of 4 gonadotropin subunit positive adenomas). On the other hand, Neuro D1 mRNA was not detected in all 5 GH-secreting adenomas or in all 3 PRL-secreting adenomas.
