TABLE 1 Comparison of Control and Alzheimer's Patients Who Received or Did Not Receive Supplemental Oxygen during the Agonal Period

From: Recovery and Expression of Messenger RNA from Postmortem Human Brain Tissue

Case

Age/Sex

PMDa (h)

RNA (μg/g)

CSF pH

Sudden Death

Postmortem Inflammation

Braak Stage

APOE

Duration AD (y)

887

70 /M

2:35

455

7.1

No

Acute BP

5

N/A

11

843

94 /F

3:19

190

5.9

No

Candidiasis

3

3,4

20

874

68/F

9:45

293

7.2

No

Acute BP

4

4,4

12

928

93/F

12:16

309

7.0

No

Acute BP

4

N/A

15

862

87/F

13:35

896

6.9

No

Acute BP

5

N/A

9

Control patients who received supplemental oxygen

673

80/F

1:10

190

6.9

No

Acute cystitis

1

3,3

0

406

77/M

1:15

325

7.7

No

Acute BP

1

2,2

0

542

81 /M

3:15

903

8.0

No

Acute BP

0

3,3

0

911

90/M

7:25

421

7.1

No

None

2

N/A

0

838

91/M

7:41

632

6.0

Yes

Chronic cystitis

1

3,3

0

787

93/F

10:38

1798

6.8

No

Acute BP

1

3,3

0

904

45/M

14:00

566

7.0

No

None

0

N/A

0

Alzheimer's patients who did not receive supplemental oxygen

901

80 /F

2:30

751

7.3

No

Acute BP

5

4,4

13

847

83 /M

9:10

358

7.0

No

Acute cystitis

3

3,3

N/A

927

59 /M

9:45

1204

7.2

No

Acute BP

5

4,4

10

845

82 /F

12:35

284

6.7

No

Acute BP

6

N/A

15

Control patients who did not receive supplemental oxygen

926

72 /F

2:00

796

7.1

Yes

None

2

3,3

0

795

81 /M

7:14

377

6.3

No

None

1

3,4

0

794

85 /M

10:07

253

6.9

Yes

None

1

3,3

0

  1. PMD, postmortem delay; BP, bronchopneumonia; N/A, not available; APOE, apolipoprotein E; AD, Alzheimers disease.
  2. aa Cases are arranged in order of increasing time of postmortem delay within each group.