FIGURE 3
Biopsy specimen evaluated for viability of HCC 2 weeks after RF therapy. A, nonneoplastic viable hepatic tissue obtained at biopsy. HE, 200×. B, HCC with eosinophilic cytoplasmic staining, suggesting ongoing necrosis. HE, 200×. C, nonablated hepatocytes shown in Figure 3A were positive for mitochondrial immunostaining, although marginal areas of the specimen stained intensely, whereas inner areas were faint. D and E, nuclei of HCC with cytoplasmic eosinophilia shown in Figure 3B were positive for both ssDNA and TUNEL, respectively. 200×. F, no mitochondrial staining was observed in HCC shown in Figure 3B. 200×.
