FIGURE 3 | Modern Pathology

FIGURE 3

From: Aneusomy 17 in Breast Cancer: Its Role in HER-2/neu Protein Expression and Implication for Clinical Assessment of HER-2/neu Status

FIGURE 3

Correlation between HER-2/neu protein expression and the genetic variables. The 189 cases are depicted based on HER-2/neu protein expression (Automated Cellular Imaging System immunohistochemistry scores) and each of the three genetic variables. The 10 cases with high polysomy 17 (≥3.76 signals per cell) are shown in closed circles, whereas all other 179 cases are shown in open circles. A, genetic variable: chromosome 17 copy number (signals per cell). B, genetic variable: HER-2/neu gene to chromosome 17 ratio. C, genetic variable: HER-2/neu gene copy number (signals per cell).

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