TABLE 1 Cases with Discordance between ACIS IHC and PathVysion FISH Assays
Chromosome 17 Signals per Cell | HER-2/neu Gene to Chromosome 17 Ratio | Subtotal | |||
|---|---|---|---|---|---|
<2.00 | ≥2.00 | ||||
HER-2/neu Gene | HER-2/Neu Gene | ||||
<4.00 Signals per Cell | ≥4.00 Signals per Cell | <4.00 Signals per Cell | ≥4.00 Signals per Cell | ||
≤1.75 | 0 (2) | 0 (0) | 2 (2) | 0 (1) | 2 (5) |
1.76–2.25 | 3 (67) | 0 (0) | 0 (0) | 4 (25) | 7 (92) |
2.26–2.75 | 2 (18) | 1 (2) | 0 (0) | 2 (17) | 5 (37) |
2.76–3.25 | 1 (12) | 0 (2) | 0 (0) | 1 (15) | 2 (29) |
3.26–3.75 | 1 (4) | 0 (5) | 0 (0) | 0 (7) | 1 (16) |
≥3.76 | 0 (1) | 0 (1) | 0 (0) | 0 (8) | 0 (10) |
Subtotal | 7 (104) | 1 (10) | 2 (2) | 7 (73) | 17 (189) |
