TABLE 3 β-Catenin Immunostaining Results and β-Catenin and APC Mutational Analysis Findings
From: Hepatic Adenomas: Analysis of Sex Steroid Receptor Status and the Wnt Signaling Pathway
Case No. | Degree of Immunostaininga | Mutation Analysis | ||||
|---|---|---|---|---|---|---|
ER | PR | AR | β-Catenin | β-Catenin | APC | |
1 | 1d | 1d | 0 | 0 | Wild type | Wild type |
2 | 3d | 1p | 1p | 0 | Wild type | 4344, T to A; 1442, CCT to CCA; no amino acid change |
3 | 1d | 2d | 0 | 0 | Wild type | Wild type |
4 | 0 | 1d | 0 | 0 | Wild type | Wild type |
5 | 1p | 0 | 1p | 0 | Wild type | Wild type |
6 | 0 | 0 | 1p | 0 | Wild type | Wild type |
7 | 0 | 0 | 0 | 0 | Wild type | Wild type |
8 | 1d | 2d | 0 | 1p | Wild type | Wild type |
9 | 2p | 2p | 0 | 0 | Wild type | 4378, A to G; 1454, AAA to GAA; lys→glu |
10 | 0 | 0 | 0 | 3d | Wild type | Wild type |
11 | 1p | 1p | 0 | 1p | Wild type | Wild type |
12 | 1d | 2d | 0 | 2p | Wild type | Wild type |
13 | 1p | 1d | 0 | 2d | Wild type | Wild type |
14 | 2p | 1p | 0 | 1d | Wild type | Wild type |
15 | 1p | 2d | 0 | 2p | Wild type | Wild type |
