TABLE 1 Clinical, Pathologic, and Genetic Characteristics of Tuberous Sclerosis Complex–Associated Clear Cell Renal Carcinomas

From: Mutational Analysis of the von Hippel Lindau Gene in Clear Cell Renal Carcinomas from Tuberous Sclerosis Complex Patients

Patient No.

Sex

VHL Mutation

3p LOH

Size (cm)a

Stage

Grade

Angiomyolipomasb

Cystsb

Recurrencec (Time of Follow-Up)

120

F

No

No

2.5

III

G4

No

Yes

No, 1 yr

353

F

No

No

13

II

G2

Yes

No

Not available

354

M

No

No

3.5

I

G4

Yes

Yes

No, 2 yr

618

F

No

No

1.8

I

G1

Yes

Yes

No, 1 yr

622

F

No

No

4

I

G3

No

Yes

No, 1 yr

628

M

No

No

3

I

G2

Yes

Yes

No, 2 yr

  1. aThe maximum dimension of the tumor.
  2. bThe presence or absence of angiomyolipomas and cysts in the resected specimen.
  3. cThere was no known disease recurrence or metastasis at the indicated follow-up times for the patients for whom follow-up information was available.
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