FIGURE 1 | Modern Pathology

FIGURE 1

From: Analysis of Octamer-Binding Transcription Factors Oct2 and Oct1 and their coactivator BOB.1/OBF.1 in Lymphomas

FIGURE 1

Expression of Oct2, Oct1, and BOB.1/OBF.1 in reactive lymphoid tissue from human tonsil. A, sections showing strong staining for Oct2 (A1), Oct1 (A2), and BOB.1/OBF.1 (A3) in germinal center lymphocytes. B, detail showing weaker expression in mantle zone lymphocytes than in germinal center lymphocytes for Oct2 (B1), Oct1 (B2), and BOB.1/OBF.1 (B3). The staining for Oct1 (B2) was strongest in mantle zone cells. C, interfollicular area displaying a majority of weakly positive Oct2 (C1) and BOB.1/OBF.1 (C3) cells. Basal layers within the epithelium expressed Oct1 (C2) and BOB.1/OBF.1 (A3) strongly, whereas Oct2 protein was missing (B1).

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