TABLE 1 Labeling Index of Pancreatic Ductal Lesions, Normal Ductal Epithelium, and Infiltrating Ductal Adenocarcinoma
Group | Pathologic Description | N | Mean (%) | Median (%) | Min (%) | Max (%) | SD |
|---|---|---|---|---|---|---|---|
Infiltrating | Invasive glands within a desmoplastic stroma | 15 | 36.99 | 35.10 | 23.93 | 53.27 | 9.06 |
Normal | Nonmucinous flattened or cuboidal epithelium without dysplasia | 15 | 0.41 | 0.49 | 0 | 1.02 | 0.34 |
PanIN-1A | Flat, mucinous epithelium without dysplasia | 20 | 0.69 | 0.46 | 0 | 3.70 | 0.87 |
PanIN-1B | Papillary, mucinous epithelium without dysplasia | 20 | 2.33 | 1.92 | 0.52 | 10.60 | 2.21 |
PanIN-2 | Flat or papillary, mucinous epithelium with mild-to-moderate dysplasia (mild-to-moderate nuclear irregularity, hyperchromasia, and loss of polarity) | 18 | 14.08 | 12.59 | 3.82 | 28.63 | 7.76 |
PanIN-3 | Flat or papillary, mucinous epithelium with severe dysplasia (marked nuclear irregularity, hyperchromasia, and loss of polarity), often with cribriforming and intraluminal “blebbing” | 18 | 22.01 | 21.73 | 5.76 | 38.94 | 9.77 |
