TABLE 1 Clinicopathological Associations of Appendiceal Carcinomas
Associated Factor | Total (n = 30) | Mucinous (n = 23) | Nonmucinous (n = 7) | P Value |
|---|---|---|---|---|
Age in y (mean ± SD) | 56 ± 12 | 56 ± 13 | 57 ± 10 | NS |
Gender (F/M) | 1.3 | 1.3 | 1.3 | NS |
Clinical Presentation | ||||
PMP | 16 (53) | 16 (70) | 0 | 0.002 |
Abdominal pain/appendicitis | 7 (23) | 1 (4) | 6 (86) | 0.00008 |
Mass | 3 (10) | 2 (9) | 1 (14) | |
Othersa | 4 (13) | 4 (17) | 0 | |
Treatment modality | ||||
Appendectomy | 12 (40) | 8 (35) | 4 (57) | |
Right hemicolectomy | 12 (40) | 7 (30) | 5 (71) | |
Cytoreduction (debulking) | 19 (63) | 19 (83) | 0 | 0.0002 |
Chemotherapy | 25 (83) | 20 (87) | 5 (71) | |
Differentiation | ||||
Well | 24 (80) | 23 (100) | 1 (14) | 0.00001 |
Moderately or poorly | 6 (20) | 0 | 6 (86) | |
Appendiceal adenoma | ||||
Present | 7 (23) | 4 (17) | 3 (43) | NS |
Absent | 6 (20) | 5 (22) | 1 (14) | |
Not assessed | 17 (57) | 14 (61) | 3 (43) | |
Rupture of the appendix | ||||
Present | 10 (33) | 7 (30) | 3 (43) | NS |
Absent | 7 (23) | 4 (17) | 3 (43) | |
Not assessed | 13 (43) | 12 (52) | 1 (14) | |
Stage | ||||
I | 0 | 0 | 0 | NS |
II | 2 (7) | 1 (4) | 1 (14) | |
III | 2 (7) | 1 (4) | 1 (14) | |
IV | 26 (86) | 21 (91) | 5 (72) | |
Metastatic sites | ||||
Omentum | 16 (62) | 16 (70) | 0 | 0.002 |
Liver | 3 (10) | 0 | 3 (43) | 0.01 |
Lung | 3 (10) | 0 | 3 (43) | 0.01 |
Spleen | 5 (17) | 5 (22) | 0 | |
Ovary | 5 (17) | 3 (13) | 2 (29) | |
Uterus | 3 (10) | 1 (4) | 2 (29) | |
Skin | 1 (3) | 1 (4) | 0 | |
Vital status | ||||
ANED | 3 | 2 | 1 | NA |
AWD | 21 | 19 | 2 | |
DOD | 4 | 1b | 3 | |
LFU | 2 | 1 | 1 | |
Survival in mo (mean ± SD) | 24 ± 18 | 26 ± 19 | 13 ± 9 | 0.0002 |
