TABLE 3 Molecular Results for p53 Mutations in CCSK Tumor Samples

From: Infrequent p53 Gene Mutations and Lack of p53 Protein Expression in Clear Cell Sarcoma of the Kidney: Immunohistochemical Study and Mutation Analysis of p53 in Renal Tumors of Unfavorable Prognosis

Sample

Exon

Nucleotide

Codon

Alteration

Base Pair Alteraction

Amino Acid Alteration

Case 4

in intron

  

ts

A → G

Upstream 9th base from codon 225

Case 6

5

511/512

162/163

is

+(1)T

Frame shift

Case 7

8

865

289

tv

CTC → CTT

Silent

  1. is, insertion; tv, transversion; ts, transition.