Jacobs DS DeMott WR Oxley DK, editors:

Laboratory Test Handbook Concise, 2nd Edition, 1348 pp, Hudson, OH, Lexi-Comp, 2002 ($35.95).

This is the second edition of the paperback version of the well-known Laboratory Test Handbook (5th edition) published for many years by Dr. Jacobs and his associates. It is a portable compendium of the most important clinical laboratory data, aimed primarily at busy clinicians and their associates.

The tests are listed alphabetically and can be found without too much effort. Nevertheless, first-time users are advised to read the page on “how to use this handbook,” which clearly outlines the standardized format followed in the presentation of all topics. The basics of each test are given in an abbreviated form, including facts about specimen collection, storage of the specimen, turnaround time, indications and contraindications, reference interval, use of the data and limitations, and current methodology. A few critical references are also included.

The book covers a wide range of laboratory tests. Common tests are covered in greater detail than esoteric tests. In many instances the tests pertaining to a particular sample, such as body fluids, bone marrow, and urine, are grouped together. Some tests are listed under the heading of a unifying clinical problem such as liver diseases or inherited diseases of metabolism. Testing for common pathogens, drugs, and toxins is given good coverage. There are numerous tables and algorithms that can be applied in the work-up of patients. When appropriate, the differences between males and females are given. Pediatric reference intervals are also included, making the book useful for pediatricians like me. The unfortunate events of September 11, 2001, make the addendum on bioterrorism especially appropriate.

I do not have enough laboratory medicine background to criticize specifics of this book, but all the endocrinology facts with which I am familiar are correct and are described in more than adequate detail. My only comment to the editors is to check on the use of the term alternative; this Latin derivative does not have a plural, used incorrectly on many pages of this otherwise very nice book.

This is probably the best short laboratory handbook currently available to practicing physicians. I anticipate that it will be used widely by residents, students, nurses, and primary care physicians as well as specialists.