FIGURE 1 | Modern Pathology

FIGURE 1

From: Immunohistochemical Pattern of MLH1/MSH2 Expression Is Related to Clinical and Pathological Features in Colorectal Adenocarcinomas with Microsatellite Instability

FIGURE 1

Analysis of microsatellite instability in colorectal adenocarcinomas using the five markers of the International Workshop of Bethesda (32) and fluorescence-based multiplex polymerase chain reaction. Fragment pattern of a high-frequency microsatellite instability tumor showing instability at all five loci examined (Lane D: tumor tissue; Lane C: corresponding normal mucosa) and of a microsatellite stable (MSS) carcinoma (Lane B: tumor tissue; Lane A: normal mucosa).

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