FIGURE 1

Expression of thymus and activation-regulated chemokine (TARC; brown) in a case of nodular- sclerosing Hodgkin's disease. TARC staining is seen as a brown cytoplasmic or perinuclear staining in neoplastic cells. No staining is observed in small or intermediate-sized cells. Inset, a classical Hodgkin/Reed-Sternberg (H/RS) cell showing strong cytoplasmic expression of TARC.