TABLE 2 Expression of Thymus and Activation-Regulated Cytokine (TARC) and CCR4 by Neoplastic Cells in Hodgkin's Disease and Non-Hodgkin Lymphoma and Expression of CCR4 by the Reactive Infiltrate

From: Differential Expression of Thymus and Activation Regulated Chemokine and Its Receptor CCR4 in Nodal and Cutaneous Anaplastic Large-Cell Lymphomas and Hodgkin's Disease

Diagnosis

TARC

CCR4

 

Paraffin

Frozen

Neoplastic cells

Reactive Infiltrate

Hodgkin's disease (HD)

    

 HD, ns

18/18

8/8

0/8

8/8

 HD, mc

6/6

ND

ND

ND

 HD, lp

3/7

ND

ND

ND

CD30+ T non-Hodgkin lymphomas

    

 Nodal ALCL ALK positive

0/12

0/4

1/4

4/4

 Nodal ALCL ALK negative

12/27

9/15

9/15

15/15

 Cutaneous CD30+ ALCL

1/11

0/5

5/5

5/5

 Lymphomatoid papulosis

2/15

1/4

4/4

4/4

  1. Cases were considered positive if >5% of the tumor cells expressed TARC or CCR4. ALCL, anaplastic large cell lymphoma; ns, nodular sclerosing; mc, mixed cellularity; lp, lymphocyte predominant; ND, not determined.
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