FIGURE 1
From: Altered Cellular Distribution of Tuberin and Glucocorticoid Receptor in Sporadic Fundic Gland Polyps
Immunohistochemical staining of normal oxyntic mucosa and fundic gland polyps (FGPs) for tuberin (A and B) and hamartin (C and D). Tuberin is normally expressed both in the nucleus and the cytoplasm in normal mucosa (A). In FGPs, tuberin is present only in the cytoplasm (B) and accumulates in large coarse granules in the parietal cells (B, inset). Nuclear and cytoplasmic immunostaining for hamartin is positive in both normal mucosa and FGPs (C and D).
