FIGURE 1 | Modern Pathology

FIGURE 1

From: Histologic and In Situ Viral Findings in the Myocardium in Cases of Sudden, Unexpected Death

FIGURE 1

Histologic and viral findings in human immunodeficiency virus 1 (HIV-1) myocarditis. A, the histologic findings at low magnification in Case 1. Note the interstitial inflammatory infiltrate. At higher magnification (B), cells with the cytologic features of macrophages are evident. Many of these cells colabeled with CD68 (not shown). HIV-1 RNA was detected in many of these cells by reverse transcription (RT) in situ polymerase chain reaction (PCR; C); the signal was lost if RNase digestion preceded the RT in situ PCR (D).

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