TABLE 2 Mean Relative mRNA Expression Levels of MMP-1, EGFR, p21, and VEGF in Fresh Tissue Biopsies of Normal, Dysplastic and Neoplastic Oral Epithelium

From: Effect of Duration of Fixation on Quantitative Reverse Transcription Polymerase Chain Reaction Analyses

 

Normal Epithelium (N = 2)

Dysplasia Epithelium (N = 3)

Squamous Cell Carcinoma Epithelium (N = 4)

 

Sample No.

Sample No.

Sample No.

Factor

1

2

1

2

3

1

2

3

4

MMP-1

0.13

0.02

0.07

8.96

1.84

2.07

0.66

24.50

5.10

EGFR

0.20

0.54

0.93

4.58

3.93

0.39

1.61

31.30

3.61

p21

4.45

0.08

0.31

16.37

4.71

16.02

0.60

0.66

0.31

VEGF

1.00

0.02

0.44

88.44

0.01

10.29

0.22

151.17

3.54

  1. All data points represent mean of triplicate runs. All points were measured relative to β-Gus. MMP-1, matrix metalloproteinase; EGFR, epidermal growth factor receptor; VEGF, vascular endothelial growth factor.
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