TABLE 1 Expressions of the Markers in Different Types of Neoplasia in the Three Different Cytologic Compartments

From: The Dichotomy in the Preinvasive Neoplasia to Invasive Carcinoma Sequence in the Pancreas: Differential Expression of MUC1 and MUC2 Supports the Existence of Two Separate Pathways of Carcinogenesis

 

PanIN

Ductal Adenoca

IPMN

Colloid Ca

 

1

2

3

Overall

 

Ad

Bor

Ca

Overall

 

MUC1

          

 Cy

0/11

3/17

8/13

11/43

86/136

0/11

2/15

10/48

12/74

0/15

 Me

0/11

2/17

0/13

2/43

99/136

1/11

2/15

16/48

19/74

0/15

 Lu

0/11

2/17

0/13

2/43

105/136

0/11

1/15

14/48

15/74

0/15

MUC2

          

 Cy

0/11

0/17

0/13

0/43

1/136

0/11

8/15

26/48

34/74

15/15

 Me

0/11

0/17

0/13

0/43

0/136

0/11

0/15

0/48

0/74

0/15

 Lu

0/11

0/17

0/13

0/43

0/136

0/11

4/15

10/48

4/74

  1. PanIN, pancreatic intraepithelial neoplasia; IPMN, intraductal papillary mucinous neoplasms; Ad, adenoma; Bor, borderline; Ca, carcinoma; Cy, cytoplasmic; Me, membraneous/apical; Lu, luminal.
  2. Numbers (X/Y), number of cases that expressed the marker in >10% of the cells/number of cases examined.