TABLE 2 Morphologic Characteristics

From: Isolated Bone Marrow Manifestation of HIV-Associated Hodgkin Lymphoma

Case No.

1

2

3

4

5

6

Degree of involvement (%)

40

90

30

70

80

30

Pattern of involvement

Nodular

Diffuse

Nodular

Nodular

Diffuse

Nodular

Amount of Reed-Sternberg cells

Rare

Discrete

Rare

Discrete

Discrete

Rare

Prevalent cells in the background

Fibroblasts

Fibroblasts

Small lymphocytes

Fibroblasts and small lymphocytes

Histiocytes

Fibroblasts; small lymphocytes

Main features in residual marrowa

Polyclonal plasmacytosis sinusoidal dilatation

Focal necrosis; sinusoidal dilatation

Prominent necrosis; vascular thrombosis

Polyclonal plasmacytosis sinusoidal dilatation

  

Amount of fibrosisb

3+

3+

4+

2+

2+

1+

  1. aIn all cases, residual bone marrow showed HIV-related myelopathy.
  2. bThe amount of fibrosis was estimated in areas not involved by HIV-HL.