TABLE 2 Immunolabeling and K-ras Mutation Analysis: Summary

From: Immunohistochemical and Genetic Analysis of Non–Small Cell and Small Cell Gallbladder Carcinoma and Their Precursor Lesions

   

Invasive Carcinoma Cases

 

Dysplasia Only Cases

In Situ Component of Non-Small Cell Carcinomas

Invasive Component

 

Low Grade

CIS

Flat

Papillary

Non-Small Cell Carcinoma

Small Cell Carcinoma

p53

0/2

3/3

7/9

3/4

17/27 (63%)

5/6 (83%)

p16

0/2

3/3

6/8

1/3

18/24 (75%)

2/5 (40%)

pRB

0/2

0/3

1/9

0/4

1/27 (4%)

4/6 (67%)

Dpc4

0/2

0/3

1/9

1/4

5/27 (19%)

0/6 (0%)

K-ras

0/2

1/3

ND

ND

8/27 (30%)

0/3 (0%)

  1. ND = not determined.
  2. The data are expressed as the number of abnormal results/number of normal and abnormal results. These data do not include the non-small cell carcinoma components associated with the small cell carcinomas.
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