FIGURE 1
From: Histopathological and Clinical Evaluation of Serrated Adenomas of the Colon and Rectum
Photomicrograph of typical serrated lesions showing some of the features examined in this study. The top panel shows a serrated adenoma with (A) serrations seen within all crypt lumens, as well as surface tufting. A higher power view (B) shows detail of surface dysplasia, as well as surface tufting (convex cytoplasmic protrusions along the luminal surface formed by several cells and separated by shallow notched indentations). The bottom panel shows a hyperplastic polyp with prominent basal crypt dilation (C) and a serrated adenoma showing marked architectural atypia, as evidenced by complex branching papillary structures (D). Hematoxylin and eosin; magnification: A = 120×, B = 360×, C = 30×, D = 24×.
