TABLE 2 Accuracy of Histological Criteria in the Diagnosis of Serrated Adenoma
From: Histopathological and Clinical Evaluation of Serrated Adenomas of the Colon and Rectum
Histological Characteristic | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) |
|---|---|---|---|---|
Characteristics alone | ||||
Surface epithelial dysplasia | 100 | 35 | 7 | 100 |
Surface mitoses | 18 | 41 | 1 | 91 |
Surface epithelial tufting | 88 | 55 | 8 | 99 |
Serration in >0% of crypts | 100 | 45 | 8 | 100 |
Serration in >20% of crypts | 100 | 65 | 11 | 100 |
Serration in >50% of crypts | 88 | 71 | 12 | 99 |
Characteristics in combination | ||||
Dysplasia and >0% serration | 100 | 81 | 20 | 100 |
Dysplasia and >20% serration | 100 | 97 | 71 | 100 |
Dysplasia and >50% serration | 89 | 100 | 94 | 99 |
