TABLE 6 Relation of the bcl6/CD10 Patterns with p53, Rb, p16, p27, bcl2, cyclin A, and cyclin B1 Expression Status

From: Increased Expression of the bcl6 and CD10 Proteins Is Associated with Increased Apoptosis and Proliferation in Diffuse Large B-Cell Lymphomas

 

bcl6+/CD10+ Pattern (n = 26)

bcl6+/CD10−, bcl6−/CD10+ and bcl6−/CD10− Patterns (n = 53)

p53+ (n = 38)

13

25

p53− (n = 41)

13

28

Rb+ (n = 74)

24

50

Rb− (n = 5)

2

3

p16+ (n = 65)

23

42

p16− (n = 14)

3

11

p27+ (n = 22)

6

16

p27− (n = 57)

20

37

bcl2+ (n = 47)

14

33

bcl2− (n = 27)

11

16

Cyclin A high expression (n = 44)

14

30

Cyclin A intermediate/low expression (n = 35)

12

23

Cyclin B1 high expression (n = 22)

11

11

Cyclin B1 intermediate/low expression (n = 57)

15

42

  1. Chi-square tests: bcl6/CD10 patterns vs p53 (P = 0.501), vs Rb (P = 0.535), vs p16 (P = 0.248), vs. p27 (P = 0.351), vs bcl2 (P = 0.240), vs cyclin A (P = 0.502), vs cyclin B1 (P = 0.062).
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