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Can loss-of-function prion-related diseases exist?

Molecular Psychiatry volume 3, pages 196–197 (1998)Cite this article

Abstract

Discovery of mutations of the PrnP gene without typical plaque formation and the characterization of two prion receptors led us to postulate a new class of prion-related disease: ‘loss of function’.

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Authors and Affiliations

  1. Department of Psychiatry, UNIFESP, Sao Paulo, 01509-010, SP, Brazil

    H B Samaia

  2. Ludwig Institute of Cancer Research, São Paulo, 01509-010, SP, Brazil

    R R Brentani

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  1. H B Samaia
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  2. R R Brentani
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Samaia, H., Brentani, R. Can loss-of-function prion-related diseases exist?. Mol Psychiatry 3, 196–197 (1998). https://doi.org/10.1038/sj.mp.4000378

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  • DOI: https://doi.org/10.1038/sj.mp.4000378

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