Figure 1



Affected sibling pair maximum likelihood scores plots (MLS, primary y-axis) across all chromosomes, under each of three diagnostic models. Also shown is the marker information content (secondary y-axis). Distances on x-axis are in centiMorgan (Kosambi). (See end of figure for colour coding.) The MLS data were generated using GENEHUNTER version 2.1 for autosomes and MAPMAKER/SIBS for the X-chromosome.