Figure 1: Circular representation of the Streptomyces coelicolor chromosome.

The outer scale is numbered anticlockwise (to correspond with the previously published map⁸) in megabases and indicates the core (dark blue) and arm (light blue) regions of the chromosome. Circles 1 and 2 (from the outside in), all genes (reverse and forward strand, respectively) colour-coded by function (black, energy metabolism; red, information transfer and secondary metabolism; dark green, surface associated; cyan, degradation of large molecules; magenta, degradation of small molecules; yellow, central or intermediary metabolism; pale blue, regulators; orange, conserved hypothetical; brown, pseudogenes; pale green, unknown; grey, miscellaneous); circle 3, selected ‘essential’ genes (for cell division, DNA replication, transcription, translation and amino-acid biosynthesis, colour coding as for circles 1 and 2); circle 4, selected ‘contingency’ genes (red, secondary metabolism; pale blue, exoenzymes; dark blue, conservon; green, gas vesicle proteins); circle 5, mobile elements (brown, transposases; orange, putative laterally acquired genes); circle 6, G + C content; circle 7, GC bias ((G - C/G + C), khaki indicates values >1, purple <1). The origin of replication (Ori) and terminal protein (blue circles) are also indicated.