Next-generation sequencing is pushing gene-expression profiling further into the digital age. But analog methods still have plenty of wind left. Nathan Blow looks at the looming battle over the cell's transcriptome.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Transcriptome of Pterospermum kingtungense provides implications on the mechanism underlying its rapid vegetative growth and limestone adaption
Scientific Reports Open Access 09 June 2017
-
Transcriptome and gene expression analysis of DHA producer Aurantiochytrium under low temperature conditions
Scientific Reports Open Access 25 September 2015
-
De novo Assembly and Characterization of the Testis Transcriptome and Development of EST-SSR Markers in the Cockroach Periplaneta americana
Scientific Reports Open Access 05 June 2015
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
References
Sultan, M. et al. Science 321, 956–960 (2008).
Cloonan, N. et al. Nature Methods 5, 613–619 (2008).
Mortazavi, A., Williams, B. A., McCue, K., Schaeffer, L. & Wold, B. Nature Methods 5, 621–628 (2008).
Dunham, I. et al. Nature 402, 489–495 (1999).
Rinn, J. L. et al. Genes Dev. 17, 529–540 (2003).
Rinn, J. L. et al. Cell 129, 1323–1329 (2007).
Guttman, M. et al. Nature doi:10.1038/nature07672 (2009).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Blow, N. The digital generation. Nature 458, 239–240 (2009). https://doi.org/10.1038/458239a
Published:
Issue date:
DOI: https://doi.org/10.1038/458239a
This article is cited by
-
Transcriptome of Pterospermum kingtungense provides implications on the mechanism underlying its rapid vegetative growth and limestone adaption
Scientific Reports (2017)
-
De novo Assembly and Characterization of the Testis Transcriptome and Development of EST-SSR Markers in the Cockroach Periplaneta americana
Scientific Reports (2015)
-
Transcriptome and gene expression analysis of DHA producer Aurantiochytrium under low temperature conditions
Scientific Reports (2015)
-
Efficient and graded gene expression in glia and neurons of primary cerebellar cultures transduced by lentiviral vectors
Histochemistry and Cell Biology (2015)
-
Transcriptomic analysis of maize mature embryos from an elite maize hybrid Zhengdan958 and its parental lines
Plant Growth Regulation (2015)