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Cancer

A wolf in wolf's clothing

Paradoxically, the CD95 receptor, a potent inducer of apoptotic cell death, is expressed on most tumour cells. Surprisingly, it turns out to be an important promoter of various cancers.

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Figure 1: CD95 signalling for apoptosis, and for tissue growth and tumour promotion.

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Green, D. A wolf in wolf's clothing. Nature 465, 433 (2010). https://doi.org/10.1038/465433a

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