Key Points
-
There is a resurge of interest in chemomechanical removal caries removal systems.
-
The improved efficacy of caries removal in vitro of NMAB by addition of urea has now been confirmed.
-
The improved formulation is suitable for removing caries in deciduous teeth.
-
The dentinal floors remaining after complete caries removal are suitable for bonding with dentine adhesive
Abstract
Objective
To further investigate the efficacy of N-monochloro-DL-2-aminobutyrate (NMAB) and NMAB containing 2M urea (NMAB-urea) as chemomechanical caries removal reagents in deciduous teeth using standardised lesions and limited applicator pressure.
Design
In vitro.
Method
Carious dentine was removed from standardised lesions in deciduous teeth using NMAB, NMAB-urea or isotonic saline (control); 50 lesions were studied with each reagent. The surface of the dentine remaining in cavities where complete caries removal was achieved was examined by light and scanning electron microscopy.
Main results
NMAB-urea (but not NMAB) gave significantly improved caries removal compared with saline. The dentine surfaces remaining after complete caries removal were irregular and approximately one third were bacterially contaminated.
Conclusions
The improved efficacy of NMAB by the addition of urea has been confirmed. Toxicity studies are still necessary prior to clinical use of this reagent.
Log in or create a free account to read this content
Gain free access to this article, as well as selected content from this journal and more on nature.com
or
References
Burke F M, Lynch E . Principles of chemochemical caries removal. In W M Tay, E Lynch (eds). General dental treatment. Churchill Livingstone, London, 1989; ch. 2.1.5: 1–11.
Burke F M, Lynch E . Principles of chemochemical caries removal. In W M Tay, E Lynch (eds). General dental treatment. Churchill Livingstone, London, 1989; ch. 2.1.6: 1–12.
Burke FM, Lynch E . Chemomechanical caries removal. J Ir Dent Assoc 1995; 41: 38–43.
Burke F M, Lynch E . Effect of chemomechanical caries removal on the bond strength of glass polyalkenoate cement to dentine. J Dent 1994; 22: 283–291.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Lynch, E. Efficacy of NMAB and NMAB-urea as chemomechanical caries removal reagents. Br Dent J 186, 176 (1999). https://doi.org/10.1038/sj.bdj.4800056a1
Published:
Issue date:
DOI: https://doi.org/10.1038/sj.bdj.4800056a1
