Key Points
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A description of a patient presenting with vCJD to a general dental practitioner.
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vCJD can present with atypical facial symptons such as paraesthesia.
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The case highlights the importance of medical history taking at each visit and the prompt referral of any patients with atypical signs and symptoms.
Abstract
This case report describes the initial presentation of variant CJD to a general dental practitioner. The case highlights the importance of prompt referral of patients presenting with a history of atypical facial symptoms.
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References
Spencer MD, Knight RSG, Will RG . First hundred cases of variant CJD: retrospective case note review of early psychiatric and neurological features. Br Med J 2002; 324: 1479–1482.
Henry C, Knight R . Clinical features of variant Creutzfeldt-Jakob disease. Rev Med Virol 2002; 12: 143–150.
Macleod MA, Knight R, Stewart G, Zeidler M, Will R . Sensory features of variant Creutzfeldt-Jakob disease. J Neurol Neurosurg Psychiatry 2000; 69: 413–414.
Will RG, Zeidler M, Stewart GE et al. Diagnosis of new variant Creutzfeldt-Jakob disease. Annals of Neurology 2000; 47: 575–582.
Zeidler M, Sellar RJ, Collier DA et al. The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease. Lancet 2000; 355: 1412–1418.
Hsich G, Kennedy K, Gibbs CJ, Lee KH, Harrington MG . The 14-3-3 brain protein in cerebrospinal fluid as a marker for transmissible spongiform encephalopathies. N Engl J Med 1996; 335: 924–930.
Hill AF, Butterworth RJ, Joiner S et al. Investigation of variant Creutzfeldt-Jakob disease and other human prion diseases with tonsil biopsy samples. Lancet 1999; 353: 183–189.
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The authors wish to acknowledge the kind support of the patient's family to allow us the opportunity to publish this report.
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Smith, A., Russell, D., Greene, J. et al. Presentation of a case of variant CJD in general dental practice. Br Dent J 197, 75–76 (2004). https://doi.org/10.1038/sj.bdj.4811468
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DOI: https://doi.org/10.1038/sj.bdj.4811468