The mechanistic details of the attachment of a small protein, ubiquitin, to other proteins are unclear. Crystal structures of the complexes formed by the E2–ubiquitin and RING E3 enzymes offer new insights. See Article p.115
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Lima, C., Schulman, B. A protein engagement RING. Nature 489, 43–44 (2012). https://doi.org/10.1038/489043a
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DOI: https://doi.org/10.1038/489043a
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