Figure 1 | European Journal of Human Genetics

Figure 1

From: No evidence for a parental inversion polymorphism predisposing to rearrangements at 22q11.2 in the DiGeorge/Velocardiofacial syndrome

Figure 1

(a) Schematic map of the 3 Mb commonly deleted region of chromosome 22q. This is not drawn to scale. The black boxes denote the position of the low copy repeat sequences flanking the 22q11 microdeletion region. [A] denotes the position of the proximal breakpoint, [D] the distal breakpoint of the 3 Mb commonly deleted region and [B] and [C] the distal breakpoints of the less frequent, smaller deletions. The cosmid probes used for FISH analysis with their respective colour codes are indicated underneath. Adapted from Shaikh et al. (2000). (b) Dual colour FISH on interphase cells showing the typical alignment of the three cosmid probes on chromosome 22q11.2.

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