Table 1 Major clinical problems in Rubinstein–Taybi syndrome (adapted from 3)
Feature | Percentage |
|---|---|
Polyhydramnios | 30 |
Neonatal respiratory problems | 51 |
Neonatal feeding problems | 80 |
Tear duct obstruction | 39 |
Strabismus | 58 |
Refractive error | 41 |
Upper airway infections | 60 |
Hearing loss | 24 |
Congenital heart defectsa | 32 |
Keloid formation | 25 |
Malignancies | 5?b |
Seizures | 23 |
Growth retardation <3rd centile | 75 |
