Abstract
With the availability of dense maps of anonymous and frequent SNPs spanning the whole human genome, genome-wide association studies are now becoming a reality. In this paper, we discuss the utility of these approaches to detect genetic risk variants involved in complex disease susceptibility and, in the best case scenario where a signal is detected, how helpful it will be to the understanding of the pathological process.
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Bourgain, C., Génin, E., Cox, N. et al. Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?. Eur J Hum Genet 15, 260–263 (2007). https://doi.org/10.1038/sj.ejhg.5201753
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DOI: https://doi.org/10.1038/sj.ejhg.5201753
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